α2-macroglobulin function of thioester-containing proteins guards Drosophila from a bacterial protease via two immune-induced peptides

Proceedings of the National Academy of Sciences, Volume 123, Issue 4, January 2026. <br/>SignificanceShenshu/Yulü peptides are evolutionary innovations that appeared in theDrosophilaSophophora subgenus with some species harboring only one peptide gene. They thus may partially mediate the adaptation to their ecological niches. Here, we find …