Fatty acid 2-hydroxylase facilitates rotavirus uncoating and endosomal escape

Proceedings of the National Academy of Sciences, Volume 122, number 36, September 2025.
Significant significant (VR) are not wrapped viruses that cause severe diarrhea in children, but the way they enter cells is not well understood. This study revealed that 2-hydroxylase enzymatic acid (FA2H) supports RV entry into host cells. FA2H …