Microglia contribute to bipolar depression through Serinc2-dependent phospholipid synthesis

Proceedings of the National Academy of Sciences, Volume 122, number 37, September 2025.
Significant microglies are involved in neuropsychiatric disorders, their role in comics remains unclear. In this study, using microglia-neuron cocultures derived from multipotent stem cells induced by bdii patients, we have identified the reduction of the serc2 …