IFN-inducible human phospholipid scramblase 1 (PLSCR1) protein restricts HIV-1 infection by inhibiting membrane fusion
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Proceedings of the National Academy of Sciences, Volume 122, number 39, September 2025.
Scramblase of human phospholipids (PLSCR1) is a gene stimulated by interferon (ISG) which inhibits viral infections by various mechanisms. Here, we identify PLSCR1 as a factor of restriction of the host which inhibits the entrance to HIV-1 by altering the membrane merger …
