Football on Thursday Night betting guide: football betting strategy, spread, total, money line, prop picks
The San Francisco 49ers travel to Los Angeles to play the Rams on Thursday night. This Football on Thursday Night betting guide will share the best football picks advice, top football props for and any ongoing Football on Thursday Night promo codes. It will also share best bets for Football on Thursday Night and football picks for the spread, money line and over/under. Bet Football on Thursday Night at FanDuel and receive $300 in bonus bets if your first wager of $5 or more wins.
Football on Thursday Night odds
Week 5 of Football on Thursday Night features two NFC West teams that are fighting for division supremacy. The 3-1 San Francisco 49ers will visit the 3-1 Los Angeles Rams at SoFi Stadium in Los Angeles. San Francisco has lost three straight to the LA but are 7-3 against the Rams over the past five years.
In the playoffs, Kyle Shanahan and Sean McVay met in the 2021 NFC Championship, which was won by the Rams.
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Key Injuries
QB Brock Purdy is questionable after re-aggravating a turf toe injury. If Purdy can’t go, Mac Jones is the backup. But Jones has been dealing with a knee sprain himself. WRs Ricky Pearsall (knee) and Jauan Jennings (ankle/rib) are also questionable. TE George Kittle remains on injured reserve. Other injury concerns include DE Robert Beal, Yetur Gross-Matos and CB Renardo Green.
For the Rams, cornerback Ahkello Witherspoon remains on IR, and safety Kamren Kinchens (shoulder) is questionable to play.
The longer list of offensive injuries for the 49ers has resulted in the Rams getting bet out from -3.5 to -5.5 on Monday.
Football on Thursday Night schedule
| Week 2 | Sept. 11 | 8:15 p.m. | Washington at Green Bay | Green Bay 27, Washington 10 |
| Week 3 | Sept. 18 | 8:15 p.m. | Miami at Buffalo | Buffalo 31, Miami 21 |
| Week 4 | Sept. 25 | 8:15 p.m. | Seattle at Arizona | Seattle 23, Arizona 20 |
| Week 5 | Oct. 2 | 8:15 p.m. | San Francisco at Los Angeles (N) | LA -5.5; Over/Under 47 |
| Week 6 | Oct. 9 | 8:15 p.m. | Philadelphia at New York (N) | |
| Week 7 | Oct. 16 | 8:15 p.m. | Pittsburgh at Cincinnati | |
| Week 8 | Oct. 23 | 8:15 p.m. | Minnesota at Los Angeles (A) | |
| Week 9 | Oct. 30 | 8:15 p.m. | Baltimore at Miami | |
| Week 10 | Nov. 6 | 8:15 p.m. | Las Vegas at Denver | |
| Week 11 | Nov. 13 | 8:15 p.m. | New York (A) at New England | |
| Week 12 | Nov. 20 | 8:15 p.m. | Buffalo at Houston | |
| Week 13 | Fri. Nov. 28 | 3 p.m. | Chicago at Philadelphia | |
| Week 14 | Dec. 4 | 8:15 p.m. | Dallas at Detroit | |
| Week 15 | Dec. 11 | 8:15 p.m. | Atlanta at Tampa Bay | |
| Week 16 | Dec. 18 | 8:15 p.m. | Los Angeles (N) at Seattle | |
| Week 17 | Dec. 25 | 8:15 p.m. | Denver at Kansas Cirty |
Football on Thursday Night betting sites and promos
Football on Thursday Night FAQ
When does Football on Thursday Night start?
Football on Thursday Night begins at 8:15 p.m. each Thursday.
What is the highest-scoring Football on Thursday Night game of all time?
On December 14, 2023, Las Vegas defeated Los Angeles (A), 63-21, for a Football on Thursday Night record of 84 total points. Las Vegas set a franchise record for points in a game (63) in the victory, which is also a single-team record for Football on Thursday Night. Aidan O’Connell threw four touchdown passes for Las Vegas, which also scored two defensive touchdowns. Las Vegas’ 63-point game is tied for the seventh-highest single-team scoring total in professional football history.
