5′-terminal glycosylation of protein-coding transcripts: An epitranscriptomic modification that prolongs mRNA lifetimes

Proceedings of the National Academy of Sciences, Volume 122, Number 41, October 2025.
ImportanceGlycosylation of macromolecules is widespread throughout biology, where its targets include internally glycosylated proteins, lipids, polysaccharides, and even some noncoding RNAs. However, glycosylation of coding proteins…