Citrullination negatively regulates the functions of the p53 protein and opposes its ubiquitination and degradation
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 122, Number 42, October 2025.
Significance This study examines the effects of citrullination, a post-translational modification catalyzed by peptidylarginine deiminase 4 (PAD4), on the tumor suppressor protein p53. The results demonstrate that PAD4 catalyzes the citrullination of p53, …
