Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors

Proceedings of the National Academy of Sciences, Volume 122, Number 43, October 2025.
ImportanceMyeloid hematopoiesis arises from myeloid hematopoietic stem cells (My-HSCs) which cause various pathological conditions ranging from hyperinflammation to cardiovascular diseases to cancer, and their prevalence increases with aging. …