A Rare Alabaster Vase Reveals the First Clear Evidence of Opium Use in Ancient Egypt


What were Egyptian alabaster jars really used for? Their stone and inscriptions were easy to study, but their contents remained hidden. A unique ship now offers a first glimpse of the interior.
A new study reveals that an alabaster vase inscribed with Xerxes once contained opium. The research, published in the Journal of Eastern Mediterranean Archeologymarks the first time that the contents of an inscribed Egyptian alabaster have been identified. The results show that opiates circulated widely in Egyptian society, appearing in both elite and everyday contexts.
“Our results, combined with previous research, indicate that opium use was more than accidental or sporadic in ancient Egyptian cultures and the surrounding lands and was, to some extent, an integral part of daily life,” Andrew J. Koh, the study’s lead author, said in a press release. “We believe it is possible, even likely, that the alabaster pots found in King Tutankhamun’s tomb contained opium, part of an ancient tradition of opiate use that we are only now beginning to understand.”
A multilingual ship of Xerxes’ empire
The star of the study is a 22-centimeter-high alabaster pot. Written in Akkadian, Elamite, Old Persian and Egyptian, it dedicates the vessel to Xerxes I, whose Achaemenid empire spanned Egypt, Mesopotamia, the Levant, Anatolia and parts of Arabia and Central Asia. A demotic note indicates that it once contained approximately 1,200 milliliters of liquid.
Intact alabaster vessels of this type are rare, probably fewer than 10 survive worldwide. They date from the reigns of Darius, Most lack clear discovery points, but their distribution suggests that they circulated as prestige objects across the Achaemenid world.
The vase entered the Yale Peabody Museum’s Babylonian collection shortly after its founding in 1911, becoming one of the first artifacts in its 40,000-piece assemblage.
Learn more: Warriors in the Roman period may have consumed narcotics before battle
Finding ancient opium
To recover the vase’s contents, the researchers used organic residue analysis, a technique perfected by the Yale Ancient Pharmacology Program. Because the vase is intact and made of calcite, they used a non-destructive “rustling” method, flushing its interior with heated ethanol to extract the compounds absorbed into the stone. A second laboratory solvent sequence captured all remaining traces.
The extracts were analyzed by gas chromatography and mass spectrometry, which detects low chemical residues. The strongest signals appeared during the first few washes – a pattern the team associates with calcite’s ability to trap and preserve oily compounds – while later washes were almost clean. Researchers identified morphine, thebaine, papaverine, noscapine, and hydrocotarnine, a suite of diagnostic opium alkaloids.
Rewriting King Tut’s Alabaster Legacy
The opium profile from the Xerxes ship reflects chemical signatures previously found in New Kingdom jars from an ordinary tomb at Sedment – evidence that spans nearly a thousand years and several social classes.
This long-running pattern raises new questions about the numerous alabaster vessels recovered from Tutankhamun’s tomb, some of which contained dark, sticky residue that early chemist Alfred Lucas could not identify and that ancient looters had carefully scraped from the jars.
“We have now discovered opiate chemical signatures that Egyptian alabaster vessels were attached to the elite societies of Mesopotamia and rooted in more ordinary cultural circumstances within ancient Egypt,” Koh said. “It is possible that these vessels are easily recognizable cultural markers of opium consumption in ancient times, just as hookahs are linked to shisha tobacco consumption today. Analyzing the contents of the pots from the tomb of King Tutankhamun would further clarify the role of opium in these ancient societies.”
Learn more: The discovery of the tomb of King Thutmose II could be the most important discovery since King Tut
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