The telomeric valine–arginine dipeptide repeat protein changes state to diffuse staining in mitosis and represses in vitro translation

Proceedings of the National Academy of Sciences, Volume 122, Number 47, November 2025.
SignificanceMammalian G-rich telomeric RNA can generate two proteins consisting of valine-arginine (VR) and glycine-leucine (GL) repetitive dipeptides. This is thought to occur via a mechanism employing RNA secondary structures to circumvent the…