The immunoproteasome regulates ILC2 responses by modulating mitochondrial capacity
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, volume 122, number 47, November 2025.
ImportanceProteasomes degrade poly-ubiquitinylated proteins. Inhibition of the constitutively expressed proteasome is toxic to cells. Immune cells express an immunoproteasome whose expression relative to the constitutive proteasome increases with their…
