The near-infrared bacteriophytochrome-derived fluorescent protein PENELOPE enables RESOLFT superresolution microscopy
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Proceedings of the National Academy of Sciences, Volume 122, Number 48, December 2025.
SignificanceReversible low-light saturable optical linear fluorescence transitions (RESOLFT) nanoscopy is particularly suitable for imaging living cells. However, currently available reversibly switchable fluorescent proteins (RSFPs) emitting in the visible…



