Potentiation of ryanodine receptor–mediated calcium release by MAPK is responsible for epidermal transformation and carcinogenesis
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 122, Number 50, December 2025.
Importance This study provides evidence that tumor promoters epidermal growth factor and ultraviolet radiation potentiate ryanodine receptor (RyR)-mediated Ca2+ release by activating the mitogen-activated protein kinase (MAPK)/ERK pathway and that…
