DIS3L2-mediated RNA surveillance and extracellular vesicle packaging prevent innate immune activation by aberrant cellular RNAs

https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c

Proceedings of the National Academy of Sciences, Volume 122, Number 51, December 2025.
ImportanceRNA surveillance pathways shape the transcriptome by silencing aberrant, unnecessary, and potentially harmful RNAs. We show that extracellular vesicles (EVs) package aberrant RNAs in competition with their degradation by DIS3L2, a cytosolic…

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