DNA mismatch repair mediated by Mlh1–Pms1 endonuclease-catalyzed mispair excision

Proceedings of the National Academy of Sciences, Volume 122, Number 52, December 2025.
ImportanceDNA mismatch repair (MMR) prevents mutations due to errors in DNA replication and suppresses the development of cancers. Previously identified mismatch excision pathways, dependent on exonuclease 1 or Rad27, appear to explain only a small…