Competition between glycine and GABAA receptors for gephyrin controls their equilibrium populations at inhibitory synapses

Proceedings of the National Academy of Sciences, Volume 122, Issue 52, December 2025. <br/>SignificanceGlycine and GABA type A receptors regulate inhibitory synaptic transmission in the spinal cord. Using single-molecule techniques, we demonstrate that the receptors compete for the same binding sites at mixed inhibitory synapses. Single …