The Plaza Hotel: Step Inside Its New 111Skin’s Spa

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New York’s iconic Plaza Hotel has temporarily hosted countless travelers and celebrities. Did you know this is where the Beatles stayed during their first visit to Manhattan in 1964? And then, of course, there is Éloïse, undoubtedly the hotel’s most famous resident. And now the hotel has a new permanent and very luxurious resident: The Plaza Hotel has partnered with world-renowned skincare authority, 111Skin, to launch 111Skin Spa/Clinic, a first-of-its-kind destination in the United States that brings together the brand’s clinically results-driven treatments in an iconic setting.

Rooted in the expertise of founder Dr. Yannis Alexandrides, renowned reconstructive surgeon, the spa/clinic offers highly personalized facial and body therapies that merge advanced clinical technology with restorative rituals. Each experience begins with an in-depth consultation to assess individual skin and wellness needs, followed by tailored treatments designed to deliver visible, long-term results, whether your goal is recovery, radiance, or a complete reset.

The image may contain lighting, reception furniture, table, store, sink and interior design.

© Simon Lewis Studio

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© Simon Lewis Studio

Situated within the historic walls of the Plaza, a space that also served as the venue for the 2026 Glamor Woman of the Year awards ceremony, the spa spans 8,000 square feet and includes relaxation lounges, state-of-the-art treatment rooms and private wellness suites. From LED light therapy and cryotherapy to hydro-infusion and regenerative facial treatment, to the brand’s signature exosomes, each element is designed to merge science and luxury.

“It’s a huge privilege,” says Dr. Alexandrides. “As an extension of my practice at [London’s] 111 Harley St., I couldn’t imagine a more appropriate setting to bring our luxurious, science-backed treatments to New York City. Sam Ioannidis, General Manager of The Plaza, adds: “By uniting innovation in longevity with our heritage of glamour, we are redefining wellness at The Plaza with the arrival of 111Skin Spa/Clinic. »

Image may contain furniture and interior design

© Simon Lewis Studio

The opening also marks a significant milestone for 111Skin, establishing its first permanent flagship in the United States. Between the Plaza Hotel’s legendary afternoon teas, the Ballroom’s iconic grand events and its status as a cultural landmark, the spa promises to be a must-visit destination.

Located in the heart of Manhattan at Fifth Avenue and Central Park South, the Plaza opened its doors on October 1, 1907. The hotel boasts 19 floors of glamor and luxury, designed after a French chateau, and was born from the minds of financier Bernhard Beinecke, hotelier Fred Sterry, and Harry S. Black, president of the Fuller Construction Company. The Plaza is now widely considered a cultural institution.

To schedule an appointment at 111Skin Spa/Clinic, call 212-872-7200 or visit 111skinspa.com.

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