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Redox robustness drives LPMO evolution
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 123, Issue 3, January 2026. <br/>SignificanceLytic polysaccharide monooxygenases have evolved to use highly oxidizing copper species for C–H bond activation while avoiding damage from autooxidation. Using ancestral sequence reconstruction and site-directed mutagenesis of resurrected …

