Nuclear MBL-1 modulates mitochondrial morphology through carnitine palmitoyltransferase in Caenorhabditis elegans with toxic trinucleotide repeats

Proceedings of the National Academy of Sciences, Volume 123, Issue 4, January 2026. <br/>SignificanceRNA repeat toxicity contributes to many degenerative disorders, yet its mechanisms remain poorly understood. While mitochondrial disruption has been implicated, its role in disease progression is unclear. This study reveals how mitochondrial …