Cellular circadian period and its deviation associate with Alzheimer’s pathology and brain aging in cognitively impaired older adults

Proceedings of the National Academy of Sciences, Volume 123, Issue 10, March 2026. <br/>SignificanceCircadian rhythms are daily cycles in physiology and behavior driven by internal biological clocks. Disruptions of these rhythms are common in aging and Alzheimer’s disease (AD), but whether intrinsic cellular clocks reflect disease processes …