Munc13 serves as a molecular filter for SNARE sorting and assembly in active zone condensates

Proceedings of the National Academy of Sciences, Volume 123, Issue 15, April 2026. <br/>SignificanceOur study reveals that the recruitment of Munc13-1 into RIM1/RIM-BP2 biomolecular condensates is not merely a localization event but a fundamental mechanism that confers transformative new functions. Within the condensate, Munc13-1 evolves …