An Octopus probe for high-performance >1,300 nm NIR-II fluorescence molecular imaging of cancer

Proceedings of the National Academy of Sciences, volume 123, number 18, May 2026.
ImportancePrecise intraoperative tumor resection is essential for cancer treatment but remains a challenge. We have developed “Octopus” (OCTP), a modular NIR-II (>1300 nm) probe targeting the folate receptor. Compared to the Cytalux clinical probe, the OCTP presents…