Synovial fibroblasts modulate endothelial activation in an acute injury-on-a-chip model

Proceedings of the National Academy of Sciences, Volume 123, Issue 20, May 2026. <br/>SignificanceDue to the clinical treatment timeframe, much is unknown about the initial cellular response within the human knee joint after an injury. This knowledge could guide early interventions to prevent injury-induced joint disease. Tissue-on-a-chip …