Synergy between membrane topography and domains to control signaling protein localization in mast cells facilitates their activation

Proceedings of the National Academy of Sciences, Volume 122, number 29, July 2025.
Importance The participation of ordered-lipid nanodomans (aka “rafts”) to target immune signage in the plasma membrane has been established. In addition, the membrane topography, in particular microvillosities, has also become a participant. Here we show how …