A granulin-positive macrophage subtype in mycobacterial granulomas alleviates tissue damage by limiting excessive inflammation

Proceedings of the National Academy of Sciences, Volume 122, Issue 31, August 2025. <br/>SignificanceGranulomas play a crucial role in the pathology of tuberculosis, but the immune environment governing their formation remains largely unknown. Here, we identified an infection-inducedgrna.2+macrophage subset within mycobacterial granulomas …