Blood–labyrinth barrier damage mediated by granzymes from cytotoxic lymphocytes results in hearing loss in systemic lupus erythematosus

Proceedings of the National Academy of Sciences, Volume 122, number 33, August 2025.
The loss of work of meaning (HL) is a common but poorly understood complication in the lupus erythematosus (LED), an autoimmune disease affecting several organs. This study reveals a mechanism behind the HL linked to LED using an induced Sle mouse model. We …