G-quadruplex stabilization induces DNA breaks in pericentromeric repetitive DNA sequences in B lymphocytes
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 122, number 34, August 2025.
Meaning-Quadruplexes are secondary DNA structures rich in guanine, found abundantly in most eukaryotic genomes. The stabilization of the G-Quadruplexes creates an obstacle for the replication of DNA, in particular in cells deficient in DNA repair. We show that G -…
