A hypoxia-responsive tRNA-derived small RNA confers renal protection through RNA autophagy | Science

Small RNAs derived from transfer RNA (TSRNA or TDR) perform a range of cellular functions. Here, we have shown that the TRNA-ASP-GTC-3′TDR, a TDR induced by hypoxia derived from the 3 ‘end of the ARNT-ASP-GTC, activated the autophagic flow in the renal cells and its silence …