A framework integrating multiscale in silico modeling and experimental data predicts CAR-NK cell cytotoxicity across target cell types

Proceedings of the National Academy of Sciences, Volume 123, Issue 5, February 2026. <br/>SignificancePredicting the activity of chimeric antigen receptor (CAR)-natural killer (NK) cells against their targets is challenging due to the diverse NK cell receptor repertoire and the integration of signals that control their activation. We present …