Lipidomic profiling of endometrial cancer using desorption electrospray ionization mass spectrometry imaging

Proceedings of the National Academy of Sciences, Volume 122, Issue 48, December 2025. <br/>SignificanceEndometrial cancer is rising globally, yet early detection remains a clinical challenge. We have applied desorption electrospray ionization mass spectrometry imaging (DESI-MSI) for lipidomic profiling of endometrial tissues, achieving 90% …