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Adipose cullin 3 mediates the antiobesity effect of pan neddylation inhibitors

https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c

Proceedings of the National Academy of Sciences, Volume 122, Issue 43, October 2025. <br/>SignificancePharmacological inhibition of Cullin RING E3 ligases (CRLs) by pan neddylation inhibitors has recently been shown to attenuate obesity, promote thermogenesis, and improve overall metabolic health in mice. However, the specific cullin proteins …

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