Adrenal lipoma formation via PI(3,4,5)P3/AKT-dependent transdifferentiation of adrenocortical cells into adipocytes

Proceedings of the National Academy of Sciences, Volume 122, Issue 37, September 2025. <br/>SignificanceTransdifferentiation—the conversion of one differentiated cell type into another—can be achieved experimentally through the introduction of exogenous transcription factors. Such experimental approaches have facilitated the elucidation of …