Antibody responses to a highly conserved peptide in HCV E2 protein correlate with chronicity or spontaneous clearance of HCV infection

Proceedings of the National Academy of Sciences, Volume 123, Issue 1, January 2026. <br/>SignificanceChronicity is a hallmark of hepatitis C virus (HCV) infection, often leading to severe liver diseases such as cirrhosis and hepatocellular carcinoma. Although progression to chronicity or spontaneous clearance is believed to be immune mediated …