ATM interaction with GRP94 modulates oncogenic receptor expression and signaling and microglial activation

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Proceedings of the National Academy of Sciences, Volume 122, Number 52, December 2025.
SignificanceAtaxia-telangiectasia (AT) is a pleiotropic genetic disorder caused by mutations in the ATM gene. Its gene product, ATM kinase, is canonically involved in the regulation of DNA damage responses. Here we describe how ATM regulates…

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