BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza

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Proceedings of the National Academy of Sciences, Volume 122, number 28, July 2025.
Meaning we identify the BCL -2 interaction killer (BIK) as a critical host factor for the replication of the influenza A (IAV) virus, revealing an IAV – Bik – β5 axis. This axis shows how viral nucleoprotein manipulates host cell machines to promote viral …

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