Φ value analysis underscores strong functional and structural compactness of the GABAA receptor

Proceedings of the National Academy of Sciences, Volume 122, Issue 38, September 2025. <br/>SignificanceUnderstanding how γ-aminobutyric acid type A receptors (GABAARs) couple ligand binding to ion channel opening is critical for elucidating the mechanisms underlying inhibitory neurotransmission. Using single-channel recordings with Φ value …