Dimerization propensity of the β1-adrenergic receptor in lipid nanodiscs probed by DEER and single-molecule spectroscopies

Proceedings of the National Academy of Sciences, Volume 122, number 38, September 2025.
Significant structural studies of the receptors coupled in protein G (GPCR), the oligomerization properties of class A GPCRs, such as β1-Adrenergic (β1ar) receptors, remain elusive. Most in vitro studies have been carried out in a detergent …