MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 122, Number 45, November 2025.
SignificanceDespite the known importance of the PIEZO2 mechanosensitive channel for innocuous touch, proprioception, mechanical pain, and interoception, direct modulators are still underexplored. Here, we identify MDFIC2, a sensory neuron enriched…
