Yeast centrosomes act as organizing centers to promote Polo kinase–mediated adaptation to persistent DNA damage

Proceedings of the National Academy of Sciences, Volume 122, Issue 27, July 2025. <br/>SignificanceDuring the adaptation response to persistent DNA damage, eukaryotic cells bearing moderate levels of unrepairable DNA lesions bypass a reversible checkpoint-mediated cell cycle arrest and resume cell division despite a compromised genome. …