Lamprey FOXN1 rescues the block of thymic epithelial cell development in the mouse Foxn1-deficient thymic rudiment

Proceedings of the National Academy of Sciences, Volume 122, Number 48, December 2025.
ImportancePrimary lymphoid organs, such as the thymus, are the cornerstone of the vertebrate immune system. Thymopoietic tissues have long been recognized in jawed vertebrates, ranging from cartilaginous fish to humans, and in jawless vertebrates, such as…