Structural insights into VRC01-class bnAb precursors with diverse light chains elicited in the IAVI G001 human vaccine trial

Proceedings of the National Academy of Sciences, Volume 122, number 33, August 2025.
Significant the development of largely neutralizing antibodies (BNAB) is a key objective of research on HIV vaccine due to their ability to target the regions kept on the virus. However, provoking such antibodies by vaccination has proven exceptionally …