Cdc42 defect reveals insights into microvilli organization and function in T cell immunity

Proceedings of the National Academy of Sciences, Volume 122, Issue 30, July 2025. <br/>SignificanceThe regulation and function of T cell microvilli remain incompletely understood. In this study, we show that Cdc42 is involved in controlling microvilli formation during the transition from the DP to SP stage, thereby enhancing antigen …