A factor integrating transcription and repression of surface antigen genes in African trypanosomes

Proceedings of the National Academy of Sciences, Volume 123, Issue 6, February 2026. <br/>SignificanceAfrican trypanosomes require antigenic variation to evade the host immune system. Individual trypanosomes express one variant surface glycoprotein (VSG) surface antigen gene from one of the largest known antigen gene families among all …