Circadian regulator REV-ERBα is a master regulator of tumor lineage plasticity and an effective therapeutic target
https://www.profitableratecpm.com/f4ffsdxe?key=39b1ebce72f3758345b2155c98e6709c
Proceedings of the National Academy of Sciences, Volume 122, Number 46, November 2025.
ImportanceTumor lineage plasticity (LP) is a major mechanism of treatment resistance and metastasis in many solid malignancies, including prostate cancer. A better understanding of the process is essential to develop an effective therapeutic intervention. …
