Circulating cell-free RNA signatures for the characterization and diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome

Proceedings of the National Academy of Sciences, Volume 122, Issue 33, August 2025. <br/>SignificanceMyalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating illness that affects millions of individuals worldwide. Despite the growing prevalence of ME/CFS, patients suffer from the unavailability of laboratory diagnostic …