Computer model locks in Chargers vs. Broncos picks, score prediction
The Denver Broncos will try to secure the AFC’s No. 1 seed when they host the Los Angeles Chargers in Week 18 of the 2025 NFL season. The Chargers don’t have much to play for beyond the playoff seed, and so they plan to rest Justin Herbert and other key starters. If Denver wins this game, the Broncos will secure first place and earn a bye into the first round of the playoffs.
Kickoff from Empower Stadium at Mile High is scheduled for 4:25 p.m. ET on CBS and Paramount+. The Broncos are 12.5-point favorites in the latest Chargers vs. Broncos odds on DraftKings and the total is set at 37.5. Before you make your own Broncos vs. Chargers picks, be sure to check out the top NFL picks from the SportsLine Projection Model, which simulates every NFL game 10,000 times.
Where to watch Chargers vs. Broncos on Sunday
When: Sunday January 4
Time: 4:25 p.m. ET
TV: CBS
Flow: Paramount+
Follow us: CBS Sports app
Chargers vs. Broncos Betting Preview
Odds: Broncos -12.5, over/under 37.5
Despite its excellent record, Denver is just 6-9-1 against the spread. Los Angeles is 8-7-1 against the spread, but had four straight coverages before losing to the Texans at home in Week 17. The Chargers are 6-9-1 in the Over while the Broncos are 7-9 in the Over.
Chargers vs. Broncos SGP
- Chargers +12.5
- Over 37.5
- RJ Harvey, anytime touchdown scorer
Bet it on DraftKings:
Model’s Chargers vs. Broncos Score Prediction, Picks
The Chargers cover the spread in 58% of model simulations and win in 27%, bringing in a value of +575 underdogs. The Over hits in 51% of simulations.
Chargers vs. Broncos Score Prediction: Broncos 25, Chargers 15
Want more NFL picks for Week 18?
You’ve seen the model’s best bets for the Los Angeles Chargers vs. Denver Broncos. Now, face the spread, total and money-line picks for every NFL Week 18 game here, all from the model that is simulated every game 10,000 times.
