Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization | Science

Telomerase ribonucleoprotein (RNP) synthesizes telomeric repeats at chromosome ends using a telomerase reverse transcriptase (TERT) and a telomerase RNA (hTR in humans). Previous structural work showed that human telomerase is typically monomeric, …