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Cryo-EM structures of GnRHR: Foundations for next-generation therapeutics

Proceedings of the National Academy of Sciences, Volume 122, Issue 25, June 2025. <br/>SignificanceGonadotropin-releasing hormone receptor (GnRHR) is crucial for reproductive health and a therapeutic target for disorders like endometriosis, prostate cancer, and infertility. This study employs cryoelectron microscopy (cryo-EM) to unravel …

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