Regulation of CD45 isoforms during human effector and memory CD8 T cell differentiation: Implications for T cell nomenclature

Proceedings of the National Academy of Sciences, Volume 122, Issue 32, August 2025. <br/>SignificanceCD45 isoforms are used to distinguish between naïve (CD45RA) and effector T cells (CD45RO), and in combination with CCR7 expression to define the canonical effector memory (CD45RO+CCR7-) and central memory (CD45RO+CCR7+) T cells subset. In …