Dodgers vs. Blue Jays World Series Game 6 odds, prediction, picks, Shohei Ohtani player props

The Los Angeles Dodgers and Toronto Blue Jays face off on Friday night in Game 6 of the 2025 World Series. The Blue Jays are on the verge of winning their first World Series since 1993. On Wednesday, Toronto defeated Los Angeles 6-1. Kevin Gausman (10-11, 3.59 ERA) starts for Toronto and Yoshinobu Yamamoto (12-8, 2.49 ERA) counts for Los Angeles. Shohei Ohtani is +196 to hit a home run and -230 to record a hit. George Springer returns to the lineup as the leadoff hitter after leaving Game 3 due to injury.

The first launch from the Rogers Center in Toronto is scheduled for 8 p.m. ET. Los Angeles is a -141 favorite on the money line (risk $141 to win $100) in the latest Dodgers vs. Blue Jays odds from DraftKings Sportsbook, with the Blue Jays as +119 underdogs (risk $100 to win $119), and the over/under is 7.5. Before making any Dodgers vs. Blue Jays picks, be sure to check out the MLB predictions and betting advice from SportsLine’s proven computer model.

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The SportsLine Projection Model simulates every MLB game 10,000 times. He entered the 2025 World Series with a winning score of 35-29 on MLB’s highest-rated picks this season. He excelled in home run prop selection this season, generating nearly 30 units of profit. Anyone tracking their MLB betting picks at sportsbooks and betting sites could have seen some solid returns.

Now the model has set its sights on the Dodgers vs. Blue Jays and has just locked in its MLB picks and predictions. You can now head over to SportsLine to see the model’s choices. Here are several MLB odds and betting lines for the Dodgers vs. Blue Jays:

Why the Blue Jays can win

Toronto enters this competition 19-8 as a local underdog, 62-41 after a win and with a 96-69 record with equal rest as its opponent. The Blue Jays have the support of the home crowd in this one and are 59-30 at Rogers Centre. First baseman Vladimir Guerrero Jr. is the team’s best hitter.

In the 2025 MLB playoffs, he has a .415 batting average with eight home runs, 15 RBIs and 27 hits. Third baseman Ernie Clement recorded a .391 batting average, along with 25 total hits, one home run and nine runs scored. In his last outing, Clement went 1 for 3 with a single and an RBI. Find out which team to support on SportsLine.

Why the Dodgers can win

Shohei Ohtani is an important player for Los Angeles. He is first on the team in home runs (8), RBIs (14) and OBP (.392) in the postseason. In this series alone, he hit three home runs with five RBIs. Yamamoto takes the mound, and he’s been light this postseason.

In 27 innings pitched, he has a 1.57 ERA, a 0.73 WHIP and an average of 8.2 strikeouts per game. The 27-year-old has allowed one run or less in three of his last four starts. Los Angeles is 11-4 in the playoffs and 94-64 as a favorite this campaign. Find out which team to support on SportsLine.

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How to make Blue Jays vs. Dodgers picks

SportsLine’s model leans on the total, projecting 8.9 runs, and projects 0.92 hits and 1.98 total walks for Ohtani. He also says that one side of the money line has all the value. You can head to SportsLine to see the model’s MLB picks.

So who wins the Blue Jays against the Dodgers, and which side of the money line has all the value? Visit SportsLine now to see which side you should jump to, all from the model that crushed its MLB picks, and find out.